Active Motif's Podcast

A lively discussion about the latest tips and techniques for epigenetics research.

1 Likes     1 Followers     1 Subscribers

Sign up / Log in to like, follow, recommend and subscribe!

A lively discussion about the latest tips and techniques for epigenetics research.
🇬🇧 English
last modified
2019-12-05 09:43
last episode published
2019-11-21 12:49
publication frequency
63.91 days
Stefan Dillinger owner   author  
Mmurray owner  
Number of Episodes
Detail page
Science & Medicine Natural Sciences



Date Thumb Title & Description Contributors

Epigenetic Mechanisms of Aging and Longevity (Shelley Berger)

In this Episode we sat down with Shelley Berger, Keynote Speaker at the "EMBO | EMBL Symposium: Metabolism Meets Epigenetics" to talk about her work on Epigenetic Mechanisms of Aging and Longevity. On how cytoplasmic chromatin fragments are involved in...
Active Motif author

Epigenetics & Glioblastoma: New Approaches to Treat Brain Cancer (Lucy Stead)

In this Episode of the Epigenetics Podcast our guest Lucy Stead from the University of Leeds provides insight into her work on intratumor heterogeneity in Glioblastoma. In order to tackle this area she uses an holistic approach including Computational ...
Active Motif author

The Past, Present, and Future of Epigenetics (Joe Fernandez, founder of Active Motif)

Joe Fernandez, the founder of Active Motif, has played a significant role in the evolution of the biotechnology industry. He’s seen where the industry has been, and he has a good idea where it’s going.  Prior to founding Active Motif in 1999, Joe was a...
Active Motif author

The interchromatin network model (Ana Pombo)

In this Episode of the Epigenetics Podcast our guest Ana Pombo from the Max-Delbrück-Center in Berlin provides insight in her work on the interplay between gene regulation and genome architecture. To do so she and her team use different state of the ar...
Active Motif author

Dosage Compensation in Drosophila (Asifa Akhtar)

Dosage compensation is an essential process to regulate the gene expression of the X-chromosome in female and male flies. Thereby the mechanism of regulation in humans and in drosophila is different. In humans one X-chromosome is randomly shut down in ...
Active Motif author

Spatial Organization of the Human Genome (Wendy Bickmore)

In recent years it has become more and more evident, that genome folding and chromatin packaging into the nucleus plays a pivotal role in the regulation of gene expression. In this Episode of our Podcast our host Dr. Stefan Dillinger spoke with Profess...
Active Motif author

Heterochromatin and Phase Separation (Gary Karpen)

Heterochromatin plays a pivotal role in organizing our genome in the nucleus and separating active from inactive genomic regions. In this Podcast Episode our Guest Gary Karpen from UC Berkely sits down with our Host Stefan Dillinger to talk about the r...
Active Motif author

Diabetes and Epigenetics (Jean-Sébastien Anicotte)

Type 2 Diabetes (T2D) is a chronic metabolic disease, which is caused by the failure of beta-cells in the pancreas and insulin resistance in peripheral tissue and characterized by high glucose levels in the blood. World-wide 382 Million people suffer f...
Active Motif author

AMP007 - Epigenetics and X-inactivation (Edith Heard)

In the seventh Episode of Active Motif's Epigenetics Podcast our host Dr. Stefan Dillinger sat down with Prof. Edith Heard, designated Director General of the European Molecular Biology Laboratory (EMBL), to talk about the challenges and goals of her n...
Active Motif author

AMP006 - Chromatin organization (Susan Gasser)

In the sixth Episode of Active Motif's Epigenetics Podcast our host Dr. Stefan Dillinger sits down with Prof. Susan Gasser, director of the Friedrich Miescher Institute in Basel, to talk about her research on heterochromatin, its localization in the nu...
Active Motif author

AMP005 - Epigenomics (Henk Stunnenberg)

In the fifth Episode of the Epigenetics Podcast of Active Motif our host Dr. Stefan Dillinger sits down with Prof. Henk Stunnenberg, full professor and head of the Department of Molecular Biology at the Radboud University in Nijmegen, to talk about his...
Active Motif author

AMP004 - Ageing and Epigenetics

The ageing population and challenges that arise from ageing are one of the great scientific challenges of this time. In the fourth Episode of the Epigenetics Podcast from Active Motif, our host Dr. Stefan Dillinger talks with Dr. Peter Tessarz from the...

AMP003 - Cancer and Epigenetics

Cancer has become one of the most dangerous diseases of the aging population of industrialized countries. Finding tools to fight cancer is hard, because Cancer represents itself as a highly heterogeneous, with over 100 types of cancers described. Cance...
Dr. Stefan Dillinger contributor

AMP002 - The Nucleosome

The Nucleosome is the basic building unit of chromatin. It consists out of 147 base pairs of double stranded DNA wrapped around the Histone core octamer that consists out of 2 copies of each dimer of H2A/H2B, and H3/H4. Nucleosomes are organized like “...
Dr. Stefan Dillinger contributor

AMP001- Multiple Challenges in ChIP

Chromatin Immunoprecipitation (ChIP) was first developed in Drosophila, where interactions of RNA Pol II with genes were investigated (Mol. Cell. Biol. August 1985 vol. 5 no. 8 2009-2018). Then, in a 1993 publication, (Genes & Dev. 1993 7:592-604),...
Dr. Stefan Dillinger contributor