Mendelspod Podcast

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Website
https://mendelspod.com/
Description
Mendelspod was founded in 2011 by Theral Timpson and Ayanna Monteverdi to advance life science research, connecting people and ideas. Influenced by the thinking tools developed by Eli Goldgratt, the founders bring a unique approach to media in the life sciences. With help from our advisors around the industry, Mendelspod goes beyond quick sound bites to create a space for probing conversations and deep insight into the topics and trends which shape the industry's future and therefore our future as a species.
Language
🇬🇧 English
last modified
2019-03-22 00:52
last episode published
2019-03-20 21:58
publication frequency
4.34 days
Contributors
managingEditor author  
Explicit
false
Number of Episodes
495
Rss-Feeds
Detail page
Categories
Science & Medicine Natural Sciences

Recommendations


Episodes

Date Thumb Title & Description Contributors
20.03.2019

Single Cell Analysis Shows Important New Detail in Key Clinical Study of AML: Koichi Takahashi, MD Anderson

The history of biomedicine goes something like this: A new tool is invented. 2. New tool is used in research labs to generate new data and new hypotheses. There is new science. 3. New tool is used in clinical setting to confirm this new science w...
ayannamv@gmail.com (Ayanna Monteverdi) author
6.03.2019

Science Communication in a Post Fact World with Erik Clausen

"That’s fake news!” We hear it all the time. And often it is said about scientific facts, for example, recent studies or evidence of global warming. Or the safeness of vaccines. But has the problem with “fake news” been that much of an issue in the...
ayannamv@gmail.com (Ayanna Monteverdi) author
28.02.2019

February 2019 Review with Nathan and Laura: Family Surprises, IQ Profiling, and Chinese Surveillance

Our two favorite commentators are back for our February 2019 month-in-review show, and to give our own twist to Valentine's Day celebrations we take on the topic of family surprises due to DNA testing. This is a phenomenon taking the world by storm in...
ayannamv@gmail.com (Ayanna Monteverdi) author
26.02.2019

Heretic No Longer? Meet Michael Joyner, Precision Medicine’s Critic-in-Chief

In 2016, after President Obama announced the Cancer Moonshot in the State of the Union, a very outspoken physician researcher from the Mayo Clinic penned an open letter to Vice President Biden criticizing the project and proposing the money be better s...
ayannamv@gmail.com (Ayanna Monteverdi) author
26.02.2019

Heretic No Longer? Meet Michael Joyner, Precision Medicine’s Critic-in-Chief

In 2016, after Obama announced the Cancer Moonshot in the State of the Union, a very outspoken physician researcher from the Mayo Clinic penned an open letter to Vice President Biden criticizing the project and proposing the money be better spent other...
ayannamv@gmail.com (Ayanna Monteverdi) author
5.02.2019

The Internet of Biology Revolution-For Real This Time, with Brett Goldsmith, Cardea

Talk to anyone who’s been around diagnostics or blood sampling for long, and they’ll tell you that nanotechnology is nothing new. Today’s guest, Brett Goldsmith, the Chief Technology Officer at Cardea, says he was involved in the nano revolution that w...
ayannamv@gmail.com (Ayanna Monteverdi) author
5.02.2019

The Internet of Biology Revolution—For Real This Time, with Brett Goldsmith, Cardea

Talk to anyone who’s been around diagnostics or blood sampling for long, and they’ll tell you that nanotechnology is nothing new. Today’s guest, Brett Goldsmith, the Chief Technology Officer at Cardea, says he was involved in the nano revolution that w...
ayannamv@gmail.com (Ayanna Monteverdi) author
5.02.2019

The Coming Internet of Biology Revolution—For Real This Time, with Brett Goldsmith, Cardea

Talk to anyone who’s been around diagnostics or blood sampling for long, and they’ll tell you that nanotechnology is nothing new. Today’s guest, Brett Goldsmith, the Chief Technology Officer at Cardea, says he was involved in the nano revolution that w...
ayannamv@gmail.com (Ayanna Monteverdi) author
31.01.2019

January 2019 Review with Nathan and Laura: Cloning, CRISPRing, DTC, and Paleogenomic Overreach

Nathan and Laura are back for the first time this year for a wild trip past cloned CRISPRd monkeys and the first gene drive in mammals. (Just that?) But first we have to deal with our hangover from the end of last year. We talk DTC and end with a dis...
ayannamv@gmail.com (Ayanna Monteverdi) author
28.01.2019

Cara O'Neill of the Cure Sanfilippo Foundation Tells Her Story

You’re a mother, and life is typical. You’re also a pediatrician. Then one day you hear that your daughter is autistic. OK. Then you get the news that, no, it’s not autism but a very rare disease called Sanfilippo Syndrome. From your training as a...
ayannamv@gmail.com (Ayanna Monteverdi) author
24.01.2019

PregSource: The NIH’s Crowdsourcing Project for Pregnancy Data with Caroline Signore

There are hundreds of pregnancy apps available. So what is unique about the NIH’s new crowdsourcing project called PregSource? “We think PregSource is different because we offer the security and reliability of having been developed at the NIH with the ...
ayannamv@gmail.com (Ayanna Monteverdi) author
16.01.2019

Meet Christian, Janos, and the New World of 3D Oncology

Today we engage in a rare discussion between a startup founder who is going beyond sequencing and working directly with cancer patient cells in 3D cultures and with one of his customers, the husband of a cancer patient. Meet Christian Regenbrecht, the...
ayannamv@gmail.com (Ayanna Monteverdi) author
8.01.2019

Has Computational Modeling for Cancer Genomics "Arrived?" with Shirley Liu, Dana Farber

It’s the question of the moment Are we living in the age of AI? Or is it still just hype? When it comes to the latest research in immuno therapy, computational modeling is helping to answer key open questions, such as which patients might respond to...
ayannamv@gmail.com (Ayanna Monteverdi) author
27.12.2018

Amy Harmon of the NYT on Race & Genetics, Women in Science

Happy Holidays! At the end of the year, we like to speak with a journalist who covers genetics about some of their stories.
ayannamv@gmail.com (Ayanna Monteverdi) author
20.12.2018

CRISPR or Not, You Can't Genetically Enhance Humans, Says Sci-Fi Author Kim Stanley Robinson

Designer babies. The term means many things to many people. To some it means kids only dressed in Gucci. Some say that by doing pre-implantation genetic screening, we are already living in the age of designer babies. Others have been holding out fo...
ayannamv@gmail.com (Ayanna Monteverdi) author
13.12.2018

The New World of Infectious Disease Diagnosis: Out in the Field with David Hong of Karius

A one month old baby is admitted to a hospital with fever. This is cause for serious alarm. The child is put on broad spectrum antibiotics. The infected area is drained and a culture run to try to identify the pathogen. The cultures come back nega...
ayannamv@gmail.com (Ayanna Monteverdi) author
3.12.2018

California Life Science Industry Steps to New Heights - the 2019 Edition with Sara Radcliffe

Sara Radcliffe can be happy--extra happy. She is the CEO of the California Life Sciences Association at a time when the state is breaking records, beating out every other state in category after category. Today Sara discusses a new report the organ...
ayannamv@gmail.com (Ayanna Monteverdi) author
3.12.2018

California Life Science Industry Soars to New Heights - the 2019 Edition with Sara Radcliffe

Sara Radcliffe can be happy--extra happy. She is the CEO of the California Life Sciences Association at a time when the state is breaking records, beating out every other state in category after category. Today Sara discusses a new report the organ...
ayannamv@gmail.com (Ayanna Monteverdi) author
29.11.2018

Nathan and Laura on CRISPRed Babies and Other November 2018 Stories

What a week! And a great time to have on our expert contributors, genomicist Nathan Pearson and genetic counselor Laura Hercher, to talk about what is reportedly a first in history: babies born with a gene altered. They'll be called Lulu and Nana. ...
online@cglife.com (cglife) author
29.11.2018

Nathan and Laura on CRISPRd Babies and Other November 2018 Stories

What a week! And a great time to have on our expert contributors, genomicist Nathan Pearson and genetic counselor Laura Hercher, to talk about what is reportedly a first in history: babies born with their genes altered. They'll be called Lulu and Na...
online@cglife.com (cglife) author
15.11.2018

Ellen Matloff on a New Digital Genetic Counseling Product for DTC Customers

If Mendelspod had an annual Product of the Year award, we'd certainly be liking for 2018 the one featured today, a digital genetic counseling product for direct-to-consumer genetic testing. Hats are off to Ellen Matloff, a genetic counselor formerly a...
ayannamv@gmail.com (Ayanna Monteverdi) author
8.11.2018

Connecting the Dots for a Community of Rare Disease Patients: Terri Klein, MPS Society

The MPS Society is a rare organization. Not just because it is an umbrella for the rare diseases that have in common lysosomal storage malfunction. But because it is one of the largest rare disease organizations in the world. Terri Klein is the CEO ...
ayannamv@gmail.com (Ayanna Monteverdi) author
2.11.2018

Keith Robison and Shawn Baker on Illumina Buyout of PacBio

Just hours after Illumina announced their buyout of Pacific Biosciences, Theral sits down with longtime sequencing Omics Omics blogger, Keith Robison, and the Chief Science Officer at sequencing marketplace, AllSeq, Shawn Baker, to discuss the news whi...
theral@verizon.net (Theral Timpson) author
1.11.2018

October 2018 Review with Nathan and Laura: ASHG Does Race, Parents Do Gene Therapy, Unsung Demons

As an election nears, the question of race and genetics has been front and center. It even prompted ASHG to take the unusual step of making a group wide statement. The three of us agree: scientists should talk more about the race question with non-s...
theral@verizon.net (Theral Timpson) author
25.10.2018

A Point-of-Care Dx Test Based on a Few Drops of Blood—Is This the Real Thing? with Danny Levner, Sight Diagnostics

Time is health. Take certain blood cancers, for instance. When a patient is seen in a doctor’s office, they are then sent to a central lab for testing and the results can take a few days. With blood cancer patients, these few days can be vital. For...
ayannamv@gmail.com (Ayanna Monteverdi) author
25.10.2018

A Point-of-Care CBC Test Based on a Few Drops of Blood—Is This the Real Thing? with Danny Levner, Sight Diagnostics

Time is health. Take certain blood cancers, for instance. When a patient is seen in a doctor’s office, they are then sent to a central lab for testing, and the results can take a few days. With blood cancer patients, these few days can be vital. Fo...
ayannamv@gmail.com (Ayanna Monteverdi) author
15.10.2018

It’s a Gold Rush in Single Cell Genomics, Says Joachim Schultze, U of Bonn

The title says it all here. Herr Professor Schultze directs a major facility that he calls a single cell genomics platform. They have most of the single cell technologies available and partner with labs from all over the world on research. Advances ...
ayannamv@gmail.com (Ayanna Monteverdi) author
2.10.2018

A Market Solution for Biospecimen Quality Standards with Matt McLoughlin, Scientist.com

We ran a series this summer highlighting one of the major issues in biomedical research: that the collection, storage, and procurement of biospecimen samples lacks any across-the-board governing standards. Various institutions adopt their own regulati...
ayannamv@gmail.com (Ayanna Monteverdi) author
28.09.2018

September 2018 with Nathan and Laura: Studying the Same Genes and the Matt Fender Story

And here we were thinking it was a slow month! We have two big stories today: first this philosophy of biology question about whether it’s a bad thing that we’ve been stuck circling the wagons ‘round the same ole genes. Is it just an economic quest...
theral@verizon.net (Theral Timpson) author
20.09.2018

Single Cell Sequencing Tailor Made for Nephrology, Says Vivek Bhalla, Stanford

Vivek Bhalla is used to the question, what’s a nephrologist? When we admitted we’d never had one on the program, he made his own admission, saying that the kinds of people who became nephrologists are the kinds of people who don’t seek out the limelig...
ayannamv@gmail.com (Ayanna Monteverdi) author
13.09.2018

It’s the Social Factors, Stupid! Lisa Suennen on Healthcare, Her Career, Digital Health Investing, and . . . Just Being Herself

She's been a highly sought after venture funder and knowledge broker in the field of digital health. STAT News wrote that upwards of 1,500 pitches crossed her desk last year at GE Ventures. But as of a couple weeks ago, it's a desk at which she's no ...
ayannamv@gmail.com (Ayanna Monteverdi) author
5.09.2018

Concerned About DTC Test Quality? Ask Two Questions, Says Daryl Pritchard, PMC

We like talking to the folks at the Personalized Medicine Coalition (PMC). They have many stakeholders and multifaceted speakers on a wide range of topics. Recently they’re open to talking more about DTC testing—as are most of the traditional diagnos...
ayannamv@gmail.com (Ayanna Monteverdi) author
31.08.2018

August 2018 Review with Nathan and Laura: The polygenic month

It’s our first show back after the summer break, and nothing has got us all buzzing about genomics again like a polygenic risk score. It even has Laura Hercher talking about the Human Genome Project doing some delivering, god forbid. CRISPR has had a...
ayannamv@gmail.com (Ayanna Monteverdi) author
21.08.2018

An International Perspective on How to Improve Biobanking with Kirstin Goldring

For the next episode in our summer series on human tissue sample quality and biobanking, we turn to a veteran biobanker in the U.K. who managed several projects there including the U.K. Parkisons’ Disease Society Brain Bank at Imperial College. Today ...
ayannamv@gmail.com (Ayanna Monteverdi) author
16.08.2018

A Seqster Preview with Founder Ardy Arianpour

As long as we’ve been doing clinical genetics, the goal has been to marry up the genetic data with phenotypic data in the electronic medical records. This has been achieved with some success and with a few of the best genetic markers at some of the ...
ayannamv@gmail.com (Ayanna Monteverdi) author
26.07.2018

Detective Stories from the Genomic War Room with Ramesh Hariharan

A book like this only comes around once in a while—one never knows from which corner. This time it was written by the CTO of a next gen sequencing data analytics company. “Every one of these cases was intense. It was just so fascinating that I had t...
ayannamv@gmail.com (Ayanna Monteverdi) author
17.07.2018

Should Biobanking Come Under CLIA? Shannon McCall, Duke

When former President Obama’s team released the paperwork for what’s become the All of Us Research Program, in the part about biobanking, the wording specified that the biobanks applying for the grants be “CLIA compliant.”
ayannamv@gmail.com (Ayanna Monteverdi) author
12.06.2018

Pharma Stepping Up, Footing the Bill for Genetic Testing & Counseling: Jordanna Mora, Alnylam

It seems to be human nature to value and pay up to hundreds of thousands of dollars for a little white pill that we can drop on the floor--and granted, can do wonders for us, but we want to pay nothing or very little to be told what is wrong with us so...
ayannamv@gmail.com (Ayanna Monteverdi) author
7.06.2018

Are We Asking Too Much of Genomics in Cancer Research? Tony Letai, Dana Farber

It’s a question we’ve asked on the program before. Are we over relying on the genomics route getting us to biomedical research paradise? Should we be putting more eggs in other baskets? After combing through lots of clinical trials data, Tony Letai ...
ayannamv@gmail.com (Ayanna Monteverdi) author
5.06.2018

I Won’t Rest Until We Have Quality Standards in Place for Biospecimens: Carolyn Compton, ASU

She’s a force of nature, and she’s back on Mendelspod. A decade ago, Carolyn Compton was hired by the NCI to solve a problem that has plagued the world of not just cancer research, but all of biomedical research. To this day, there are no standards i...
ayannamv@gmail.com (Ayanna Monteverdi) author
1.06.2018

May 2018 with Nathan and Laura: The Free Exome, California Database, and Mosaicism

Nathan Pearson and Laura Hercher are back for a look over a busy month of headlines. May took us into the era of the free genome as Geisinger planted the genomic medicine flag on an even higher peak. And did you know California was keeping a genetic ...
ayannamv@gmail.com (Ayanna Monteverdi) author
24.05.2018

Has Diagnostic Testing Plateaued? Alka Chaubey, Greenwood Genetic Center

If you’ve been in the field of genetic testing then you know about the Greenwood Genetic Center. With an address on Mendel Circle in Greenwood, South Carolina, this non profit diagnostic testing laboratory has basically written the book on diagnosing ...
ayannamv@gmail.com (Ayanna Monteverdi) author
17.05.2018

A New Way for DTC? Nathan Pearson, Root Deep Insight

You know him, but do you know what he does for a day job? Over the past two years, Nathan Pearson has dazzled us with his broad knowledge of the genomics space on our regular monthly reviews. Today we’re talking to Nathan about his new company that h...
ayannamv@gmail.com (Ayanna Monteverdi) author
10.05.2018

Genetic Testing in the Age of Trump: Hank Greely, Stanford

"In a world turned upside down, this is an area where I don’t think he’s had much effect. I don’t think he knows how to spell “DNA.”" So begins Hank Greely in today’s interview on genetic testing in the age of Trump. Hank is a Professor of Law and,...
ayannamv@gmail.com (Ayanna Monteverdi) author
3.05.2018

Genetic Testing is Dead, Long Live Genetic Testing: Sean George of Invitae

A few years ago they were the new kid on the block, and now they are a leader of mainstream genetic testing. Last year their revenue and profit were significantly up. And yet in today’s interview, CEO Sean George does not sound like someone sitting b...
ayannamv@gmail.com (Ayanna Monteverdi) author
1.05.2018

April 2018 with Nathan and Laura: Golden State Killer and the Cancer Prediction Space

After decades on the loose, it’s cool the cops finally caught him. But is it cool how they caught him? Nathan Pearson and Laura Hercher are back for April’s headlines. AACR had some more good news about Keytruda, and we take a look at the cancer pre...
ayannamv@gmail.com (Ayanna Monteverdi) author
24.04.2018

Liquid Biopsy for Infectious Disease with Mickey Kertesz, Karius

Sequencing goes to the world of infectious disease.
ayannamv@gmail.com (Ayanna Monteverdi) author
18.04.2018

Nanopore Sequencing and the Future of Cancer Research with Chia-Lin Wei, JAX

We can all recognize that PacBio has laid down the railroad tracks in the frontier of long read sequencing. What many are asking this year is how close on their caboose is Oxford Nanopore? Chia-Lin Wei is the Director of Genome Technologies at the Ja...
ayannamv@gmail.com (Ayanna Monteverdi) author
10.04.2018

A New Method for Long Reads: Hanlee Ji of Stanford on Cancer Genomics Tech 2018

Hanlee Ji is the Senior Associate Director of the Stanford Genome Technology Center as well as an oncologist at Stanford. He’s also a clinical geneticist. In other words, he doesn’t need to take off his glasses and spin around in a phone booth to be ...
ayannamv@gmail.com (Ayanna Monteverdi) author
2.04.2018

March 2018 in Genomics with Nathan & Laura: DTC BRCA and Revisiting All of Us

23andMe steals the headlines yet again. “If somebody is worried about breast cancer susceptibility in their family, they should certainly not be using this test.” That’s our monthly commentator and genetic counselor, Laura Hercher, talking about BRCA...
ayannamv@gmail.com (Ayanna Monteverdi) author